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Also how long is it active in your system after taking it?

If someone is taking Vicodin for pain after surgery, but has a really bad reaction to it, what are some other painkillers he might recommend?

I’m writing a story with this scenario as a small bit of the plot, for a class. I’d really just like a straight answer rather than comments about possible suicide attempts. Assume there was overwhelming evidence that it was, in fact, accidental. And thanks for any help, people with more medical knowledge than me!
Thanks for the aspirin suggestion. I did wonder if it was plausible to accidentally overdose on acetaminophen.